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5 Combined ferroptosis-cuproptosis strategy for OSCC The extensive crosstalk between ferroptosis and cuproptosis across metabolic and signaling networks furnishes a strong mechanistic rationale for their simultaneous induction

Calvello R, Aresta A, Trapani A, Zambonin C, Cianciulli A, Salvatore R

TMAO t 1/2 was estimated by fitting linear regression to log-transformed concentrations over the final three time points of each curve, corresponding to the terminal elimination phase, following standard log-linear pharmacokinetic modeling methods

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Rodent studies in ulcerative colitis show significant reduction in mucosal inflammation with oral or rectal KPV administration